Body odor, especially underarm odor, is often a sensitive topic for many people. But did you know that the cause of underarm odor isn’t just about hygiene? It’s also related to genetics! One of the key genes that play a significant role in this is the ABCC11 gene.
What Is the ABCC11 Gene?
You might be wondering, what exactly is the ABCC11 gene? The ABCC11 gene is responsible for regulating the production of a protein that influences the composition of the fluid produced by apocrine glands. These glands, located in areas like the underarms and groin, produce a fluid rich in lipids and proteins. Initially, this fluid is odorless, but when skin bacteria break it down, the distinctive underarm odor emerges. The role of the ABCC11 gene here is to determine whether a person has apocrine glands that produce this fluid in large amounts or barely any at all.
The Link Between the ABCC11 Gene and Underarm Odor
So, how is the ABCC11 gene a direct cause of underarm odor, or lack thereof?
Research has shown that people with a specific genetic variation in the ABCC11 gene (variant rs17822931) are less likely to have underarm odor. This variation is more commonly found in East Asian populations, where around 80–90% of people carry this genetic trait, making them less likely to produce underarm odor. In contrast, this genetic variation is much rarer in European and African populations, where underarm odor is more prevalent. If you’d like to explore this topic further, you can access the research journal here.
Fascinating Facts About the ABCC11 Gene
Not Just Underarm Odor
The ABCC11 gene is also associated with earwax type. People without underarm odor typically have dry earwax, while those with underarm odor tend to have wet earwax.
Genetic Evolution
Scientists believe that the mutation in the ABCC11 gene, which reduces underarm odor, is the r result of evolutionary adaptation. One theory suggests that a lack of body odor may have provided social advantages in certain human groups.
Personal Care Products
This discovery explains why products like deodorants or antiperspirants are more commonly used in Western regions compared to East Asia. In East Asia, the need for such products is relatively low due to the prevalence of the odorless ABCC11 variation.
The discovery of the ABCC11 gene has opened doors for developing more personalized body care products. Additionally, this information can help people understand that body odor isn’t merely a hygiene issue but a genetic factor that cannot always be controlled.
The ABCC11 gene is a prime example of how genetics shape unique aspects of the human body, including underarm odor. By understanding the role of this gene, we can reduce the stigma around body odor and focus on finding solutions tailored to individual needs.
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